![]() ![]() They united for their common goal, and created the Mise-Nishikawa method which is still what most grafting technicians use today. Meanwhile, Nishekawa applied for a nucleation patent of his own, and discovered Mise’s patent in the patent office. The special grafting needle that Mise invented was granted a patent in 1907. ![]() At about that same time, a government biologist, Tokichi Nishikawa and a carpenter, Tatsuhei Mise had both been working with pearl formation and also successfully nucleated the Akoya pearl oyster. Kokichi Mikimoto, considered the father of the modern cultured pearl industry, began experimenting with nucleating Akoya pearl oysters and was finally successful in cultivating pearls after nearly a decade of experimentation. The science of getting an oyster to cultivate a pearl began in the early 1900’s in Japan.
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